WuXi AppTec Job Openings in Plainsboro, NJ

 WuXi AppTec Job Openings in Plainsboro, NJ

药明康德 WuXi AppTec

药明康德新药开发有限公司，是全球领先的制药、生物技术以及医疗器械研发外包服务公司，在中美两国均有运营实体。作为一家以研究为首任，以客户为中心的公司，药明康德向全球制药公司、生物技术公司以及医疗器械公司提供一系列全方位的实验室研发、研究生产服务，服务范围涵盖从药物发现到推向市场的全过程。 

 WuXi AppTec is a leading global pharmaceutical, biopharmaceutical, and medical device outsourcing company with operations in China and the United States. We provide a broad and integrated portfolio of laboratory and manufacturing services and play an ever-expanding role in helping our customers discover and develop life-saving medicines and products for patients. Since its establishment in 2000, WuXi AppTec has grown to over 3 million square feet of laboratory and manufacturing space, with more than 7,000 talented, dedicated employees. Our rapid business expansion has opened up many exciting positions across the company and around the world.

If interested in applying for any of these roles, please apply at www.wuxiapptec.com

Associate Scientist I

Primary Duties and Responsibilities:

 ·       With minimal supervision after training, individual performs routine laboratory techniques (e.g. biological sample processing, HPLC analysis, in vitro metabolism incubations, drug and drug interations, radiolabel isotope ¹⁴C and ³H handling.)

 ·       Receive specific instructions on assigned task and expected results.

 ·       Maintain research notebooks in a well-organized manner.  All necessary documentation is recorded.

 ·       Perform routine calculations, tabulate and record results.

 ·       Prepare standard solutions used in the laboratory.

 ·       Prepare accurate data summary with minimal supervision.

 ·       Maintain and calibrate laboratory equipment.

• Assume responsibility for technical accuracy of work.
• Learn and enhance technical knowledge of pharmaceutical areas, metabolism chemistry, and/or environmental.
• Comply with all safety rules, practice good housekeeping, and maintain safe workplace without supervision.

• Understanding of Good Laboratory Practices and EPA, FDA, or other regulation pertaining to the study.
• Promote implementation and compliance with WuXi/ XBL safety policies, practices, and procedures in order to maintain a safe work environment and minimize or eliminate injury.
• Other duties as assigned.

Experience / Training / Education:

·       Bachelor’s degree in chemistry, biology, or a related discipline

·       0-2 years of relevant experience, or equivalent

·       Any similar combination of education and experience

Knowledge / Skills / Abilities:

·       Ability to perform preliminary lab work independently after training

·       Ability to follow instructions to perform required procedures

·       Knowledge of commonly used concepts, practices, and procedures within biological or chemical R&D laboratory setting

·       Well organized, detail oriented, and adaptable to changes

·       Effective oral and written communication skills

·       Effective interpersonal skills

·       Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint

·       Good time management skill in order to perform of multiple projects within deadlines

·       Ability to effectively prioritize workload and manage changes in direction

·       Ability to work in a team environment

·       Familiarity with and adherence to regulatory guidelines consistent with WuXi/XBL requirements

Staff Scientist

Primary Responsibilities

• Prepare dose formulation for animal dosing and perform dose formulation analysis. 
• Plans and carries out experiments and associated research assignments, e.g. biological sample processing, in vitro/in vivo metabolism studies, metabolite profiling and identification, drug and drug interactions, etc. 
• Handle radio-labeled materials (e.g., ³H, ¹⁴C). 
• Efficient time management to complete the assigned task
• May act as study director/principal investigator.
• Operates and/or oversees the operation of equipment to acquire experimental data.
• Compiles, calculates, plots, and analyzes, and with experience, interprets data; records and maintains data in accordance with accepted standards and practices.
• Assumes responsibility for technical accuracy of work.
• Thorough understanding of Good Laboratory Practices and EPA, FDA, or other regulations pertaining to the study.
• Promotes implementation and compliance with WuXi / XBL safety policies, practices, and procedures in order to maintain a safe work environment and minimize or eliminate injury.
• Maintains and enhances technical expertise and knowledge of environmental, metabolism chemistry, and/or pharmaceutical areas.
• Identifies safety hazards and initiates corrective action.  Assists in the safety training for subordinates and/or less experienced staff.
• Assists in training Associate Scientist, Assistant Scientist, and Laboratory Assistant. 
• Collaborate with other scientists in a team to support metabolism studies. 
• Other duties as assigned.

Experience / Training / Education:

·       Bachelor’s or MS degree in chemistry, pharmaceutical, or a related discipline

·       5-7 years of relevant experience with advanced responsibilities in research and development, or equivalent

·       Any similar combination of education and experience

Knowledge / Skills / Abilities:

·       Experience with formulation and radioisotope handling (e.g., ³H, ¹⁴C).

·       Experience and knowledge of in vivo and in vitro metabolism.

·       Basic knowledge of commonly used scientific concepts, practices, and procedures within a biological or chemical R&D laboratory setting

·       Highly motivated with excellent communication and organizational skills

·       Well organized, detail oriented, and adaptable to changes

·       Effective oral and written communication skills

·       Effective interpersonal skills

·       Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint

·       Ability to work under pressure of multiple projects and deadlines

·       Ability to effectively prioritize workload and manage changes in direction

·       Ability to work in a team environment

·       Familiarity with and adherence to regulatory guidelines consistent with WuXi / XBL requirements

  Research Scientist

Primary Duties and Responsibilities:

·       Identification of drug metabolites using liquid chromatography-tandem mass spectrometry, NMR, and other analytical methodologies. 

·       Elucidation of metabolic pathways involves the identification and quantification of metabolites in biological matrices (e.g., blood, plasma, excreta) using HPLC with radioactivity detection and/or LC-MS/MS. 

·       Conduct in vivo and in vitro metabolism studies. 

• Conduct LC-MS/MS analysis and interpretation. 

·       Handle radio-labeled materials (e.g., ³H, ¹⁴C). 

·       Serve as Study Director/Principal Investigator. 

·       Implements new techniques and instrumentation to improve technical operations.

·       Prepares scientific reports that document the analytical results and interpretation for the identification of drug metabolites. 

·       Authors scientific papers, which are published in peer reviewed journals, and presented in scientific meetings. 

·       Collaborate with other scientists in a team to support metabolism studies. 

·       Knowledge of in-vitro and in-vivodrug metabolism processes and related bioanalytical techniques. 

Training / Education:

·       Ph.D. degree in a chemical, pharmaceutical, or equivalent

·       Post-doctoral experience is desirable

·       Any similar combination of education and experience

Experience / Knowledge / Skills / Abilities:

·       Experience in structural characterization and identification of drug metabolites using LC/MS/MS.

·       Experience and knowledge of in vivo and in vitro metabolism.

·       Experience with radioisotope handling (e.g., ³H, ¹⁴C) biochemical techniques is a plus.

·       Experience and knowledge in design of NMR experiments, operation, and data interpretation as applied to identification of unknowns is a plus.

·       Experience and knowledge in agrochemical and animal health areas is a plus.

·       Basic knowledge of commonly used scientific concepts, practices, and procedures within a biological or chemical R&D laboratory setting

·       Highly motivated with excellent communication and organizational skills

·       Well organized, detail oriented, and adaptable to changes

·       Effective oral and written communication skills

·       Effective interpersonal skills

·       Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint are desirable

·       Ability to learn quickly and effectively in a dynamic laboratory environment

·       Ability to follow instructions and research plans with limited supervision

·       Ability to work in a team environment

·       Ability to understand and adhere to regulatory guidelines consistent with WuXi / XBL requirements

 Research Scientist – MET ID

Primary Duties and Responsibilities:

• Identification of drug metabolites using liquid chromatography-tandem mass spectrometry, NMR, and other analytical methodologies.
• Elucidation of metabolic pathways involves the identification and quantification of metabolites in biological matrices (e.g., blood, plasma, excreta) using HPLC with radioactivity detection and/or LC-MS/MS.
• Conduct in vivo and in vitro metabolism studies.
• Conduct LC-MS/MS analysis and interpretation.
• Handle radio-labeled materials (e.g., ³H, ¹⁴C).
• Implements new techniques and instrumentation to improve technical operations.
• Prepares scientific reports that document the analytical results and interpretation for the identification of drug metabolites.
• Authors scientific papers, which are published in peer reviewed journals, and presented in scientific meetings.
• Collaborate with other scientists in a team to support metabolism studies.
• Knowledge of in-vitro and in-vivo drug metabolism processes and related bioanalytical techniques.

Training / Education:

• Ph.D. degree in a chemical, pharmaceutical, or equivalent
• Post-doctoral experience is desirable
• Any similar combination of education and experience

 Experience / Knowledge / Skills / Abilities:

• Experience in structural characterization and identification of drug metabolites using LC/MS/MS.
• Experience and knowledge of in vivo and in vitro metabolism.
• Experience with radioisotope handling (e.g., ³H, ¹⁴C) biochemical techniques is a plus.
• Experience and knowledge in design of NMR experiments, operation, and data interpretation as applied to identification of unknowns is a plus.
• Basic knowledge of commonly used scientific concepts, practices, and procedures within a biological or chemical R&D laboratory setting
• Highly motivated with excellent communication and organizational skills
• Well organized, detail oriented, and adaptable to changes
• Effective oral and written communication skills
• Effective interpersonal skills
• Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint are desirable
• Ability to learn quickly and effectively in a dynamic laboratory environment
• Ability to follow instructions and research plans with limited supervision
• Ability to work in a team environment
• Ability to understand and adhere to regulatory guidelines consistent with WuXi/ XBL requirements

Associate Quality Assurance Specialist

Primary Duties and Responsibilities:

• Maintains a current awareness of EPA, FDA, and OECD Good Laboratory Practice (GLP) regulations and any other related Regulations which may apply to WuXi/XBL activities.
• Evaluates current laboratory practices. Recommends changes or modifications to laboratory procedures in order to facilitate compliance with GLP standards.
• Conducts audits (protocol/plan, raw data, and final report audits for accuracy and completeness, verifying that the final reports accurately reflect the raw data generated) and in-lab critical phase inspections of any GLP-regulated study performed at the laboratory for conformance to the final protocol/plan, SOPs, and relevant GLP regulations.
• Conducts inspections of laboratories/facilities
• Conducts audits of employee training files.
• Prepares written records of all inspections and audits. Submits findings to the study director,and/or principal investigator (or laboratory supervisor, when appropriate) and management, indicating deviations from or conformance with GLPs, protocol/plan, methods and SOPs.
• Reports periodically to QA management regarding quality issues and status of inspection/audit activities.
• Assists in reviewing, writing, and maintaining up-to-date SOPs and controlled documents for the QA unit.
• Updates the master schedule as required by GLPs.
• Other duties as assigned by QA management
• May be required to assist in other departments

Experience / Training / Education:

• Bachelor’s degree in biology, chemistry, or related field.
• At least 2 years of experience in QA or QC, with focus on bioanalytical
• Familiarity with Good Laboratory Practice standards and experience working in a GLP regulated research environment.
• Any equivalent combination of education and experience

 Knowledge / Skills / Abilities:

• Knowledge of EPA, FDA, and OECD Good Laboratory Practice (GLP) regulations and commonly used concepts, practices, and procedures within GLP QA field
• Must work well with numbers
• Detail-oriented and highly organized
• Effective oral and written communication skills
• Excellent interpersonal skills
• Computer skills: working knowledge of Internet, MS Word, Excel, Outlook, SharePoint and PowerPoint
• Ability to multitask and work under pressure of multiple projects and deadlines
• Ability to effectively prioritize workload and manage changes in direction
• Must be able to record and keep essential records for a regulated environment
• Familiarity with and adherence to regulatory guidelines consistent with WuXi/XBL requirements

If interested in applying for any of these roles, please apply at www.wuxiapptec.com